How does a person's level of immune activity affect AIDS?
Perhaps last, and maybe not least, we talked before about an over-activated immune system, a heated up immune system. People exposed more to parasites, and to other infectious agents, as occurs in parts of Africa, particularly equatorial Africa, have a more heated up immune reactivity. When your immune system is more activated, more heated up, more virus can spread, more virus will replicate itself, reproduce itself. You'll have a higher, tighter virus. It'll be easier for you to transmit that virus to someone else. So the contribution of other infectious diseases to AIDS, just as AIDS contributes to other infectious diseases, making TB take off. If you're HIV infected and you have TB, your TB is much worse, and much more spreading. On the other hand if you have other infections that are activating your immune system those infections make HIV worse, more replicating, more easy to transmit.