What's the connection between histamine and itching?

What's the connection between histamine and itching?

Daniel Behroozan (Dermatologist) gives expert video advice on: What is an 'itch'?; What's the connection between histamine and itching?; When does itching indicate a serious condition? and more...

There's a very simple connection between histamine and itching. In the blood there are certain cells that will release histamine when stimulated, that will then activate nerves in your skin, that will transmit a message to your brain that there is an itch, and your brain will then cause you to scratch.