How will EOquin work?

How will EOquin work?

EOquin is an interesting drug. It is an analog of a chemotherapy drug called Mitomyacin C, that has been around for many years. What seems to be unique about EOquin is that it is often referred to as a pro-drug. EOquin, by itself, is not active. There are certain enzymes that are found in primarily bladder cancer, which activate the drug in an environment that's oxygen-free. The bladder is an ideal target for it, because it's oxygen-free, and bladder cancer elicits the particular enzyme that activates the drug. What's also interesting about EOquin is that when you look at the chemical structure of it, it's a large structure, and by virtue of the fact that it's a large structure, it's not absorbed through the bladder. We've completed and reported on a study here at Spectrum that has looked at immediate post-operative installation of EOquin that was retained for an hour and, during that time point, and after, blood levels were drawn in 20 subjects, looking to see if there was any detectable EOquin in the blood stream, and neither EOquin nor any of its metabolized were detected. Although EOquin is a chemotherapeutic agent, since it doesn't get into the systemic circulation, you will not get the nausea, vomiting, hair-loss and similar symptoms that most patients associate with chemotherapy.