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HIV Drug Resistance

 
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HIV Drug Resistance

What is HIV 'drug resistance'?

HIV drug resistance just means that the HIV has developed resistance and can grow in the presence of one or more of the anti-retro viral drugs. This virus has a tremendous capacity to develop resistance mainly because it mutates very, very, rapidly, and as it divides it makes lots of genetic mistakes which throw up lots of different types of viruses. Some of those types will grow in the presence of the drugs and then you have HIV drug resistance.

How do doctors test for HIV drug resistance?

We can test for HIV drug resistance with tests called genotypes or phenotypes. The genotype test looks at the genetics of the virus to see if the virus has developed mutations of certain genes, which we have come to know are associated with resistance to certain HIV drugs. The phenotype test grows the virus in the laboratory in the presence of the HIV drugs to see if they no longer work. And if they no longer work in the laboratory against the HIV virus, then the virus is resistant.

How do I prevent HIV drug resistance?

You can prevent developing HIV resistance by taking your drugs regularly at the full dose. If someone, for example, makes a mistake and takes one pill instead of two of a certain antiretroviral they may get develop HIV drug resistance, because there's inadequate drug in the blood to fully suppress the HIV virus. When the virus is growing in the presence of inadequate concentrations an HIV drug, the virus can “learn”, or can rapidly produce mutants that will grow up and be resistant to the drug. To prevent HIV drug resistance, take your drugs at full dose regularly, and don't stop them, and don't have interval interruptions.

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Dr. Charles Farthing
Meet the Expert
aidshealth.org
  • What is HIV 'drug resistance'?
  • How do doctors test for HIV drug resistance?
  • How do I prevent HIV drug resistance?
more ...
HIV Treatment
 HIV Treatment Basics 
  1. Dr. Charles Farthing
  2. How is HIV treated? 
  3. If I live in a small town, where can I find HIV treatment? 
  4. When can I begin treatment for HIV? 
  5. Is it ever necessary to start treatment if my CD4 count is higher than 350? 
  6. How many pills do I have to take during my HIV treatment? 
  7. Why would my HIV medication need to be changed? 
  8. Can my HIV medication bring my viral load down? 
  9. How long can I expect to live if I take HIV medication? 
  10. Are alternative treatments effective in battling HIV? 
  11. Is it safe to buy HIV medication sold without a prescription? 
  12. How much does HIV medication cost? 
 HIV Treatment And Combinations 
  1. Dr. Charles Farthing
  2. What are 'nucleosides'? 
  3. What are 'non-nucleosides'? 
  4. What are 'protease inhibitors'? 
  5. What are 'CCR5 entry inhibitors'? 
  6. What is 'HAART' or 'cocktail medications'? 
  7. How effective is HAART compared to the original HIV medication? 
  8. What is a typical combination of HAART? 
  9. How do I choose which medication to take for my HIV? 
  10. What is 'Atripla'? 
  11. Is Atripla as effective as the traditional cocktail medication? 
  12. Should I switch to Atripla if I am already on HAART? 
 HIV Treatment Side Effects 
  1. Dr. Charles Farthing
  2. What are the risks of HIV medications? 
  3. What are the most common side effects of HIV medications? 
  4. What are the most serious side effects of HIV medication? 
  5. What's the best way to deal with nausea and vomiting due to HIV medication? 
  6. What are 'body shape changes' that occur with HIV medication? 
  7. How can I combat body shape changes due to HIV medication? 
 Adherence To HIV Treatment 
  1. Dr. Charles Farthing
  2. How can 'accepting' the fact that I have HIV help me with my medical treatment? 
  3. Why is 'adherence' important during my HIV treatment? 
  4. What can I do to help me be more adherent to my HIV medication? 
  5. Can I stop my treatment if my HIV medication makes me ill? 
  6. What are some major causes of non-adherence to HIV medication? 
  7. How can HIV doctors assist people who use crystal meth? 
HIV Drug Resistance (Now Playing)
  1. Dr. Charles Farthing
 HIV Doctors 
  1. Brett Grodeck
  2. What type of medical specialist do I need if I am HIV positive? 
  3. What should I look for in an HIV doctor? 
  4. How do I find an HIV doctor? 
  5. When should I make my first HIV appointment? 
  6. What should I expect at the first appointment with my HIV doctor? 
  7. What questions should I ask my HIV doctor during my first appointment? 
  8. Will my HIV doctor put me on medication immediately? 
 HIV And Insurance 
  1. Brett Grodeck
  2. Will I lose my health insurance if I have HIV? 
  3. Are there special insurance programs for people with HIV? 
  4. Will I be able to get health insurance if I have HIV? 
  5. Who can help me get or maintain insurance if I have HIV? 
  6. Can I get life insurance if I have HIV? 
  7. Can I get disability insurance if I have HIV? 
 AIDS Drug Assistance Program 
  1. Brett Grodeck
  2. What is the 'AIDS Drug Assistance Program' or ADAP? 
  3. Do all states have an ADAP program? 
  4. How do I learn more about my state's ADAP program? 
 HIV Clinical Trials 
  1. Brett Grodeck
  2. What are HIV 'clinical trials'? 
  3. What are the benefits of joining an HIV clinical trial? 
  4. What are the disadvantages of joining an HIV clinical trial? 
  5. Where can I learn more about HIV clinical trials? 
 New HIV Medicine 
  1. Brett Grodeck
  2. What is the goal of taking HIV medicine? 
  3. What new HIV medicines should I ask my doctor about? 
  4. Why are the new HIV medicines better? 
  5. How will the new HIV medications help me be adherent? 
 Taking HIV Medication 
  1. Brett Grodeck
  2. How do I know if I can manage my HIV medication regimen? 
  3. What is a routine I can use in order to stay adherent? 
  4. Will I feel ill every time I start a new HIV medication? 
  5. Can I take HIV medication with alcohol or other drugs? 
  6. Should I tell my doctor if I skip my medicine? 
  7. What if my doctor puts me on a very difficult HIV regimen? 
 HIV Treatment Failure 
  1. Brett Grodeck
  2. How can I get sick if HIV medicine works so well? 
  3. What is a 'viral blip'? 
  4. Should I be worried if I have a viral blip? 
  5. Why would I get two or three viral blips in a row? 
  6. Is treatment failure a sign of a serious problem? 
  7. What is 'salvage therapy'? 
  8. Is it possible to be healthy again after having treatment failure? 
 HIV Vaccines 
  1. Dr. Robert Gallo, M.D.
  2. Can humans develop a resistance to HIV infection? 
  3. Why is a vaccine critical in the fight against HIV? 
  4. What are the obstacles to an HIV vaccine? 
  5. Why is HIV a difficult virus to vaccinate against? 
  6. Are there any approved vaccines for HIV in the market? 
  7. How can a successful HIV vaccine be created? 
  8. Will I be at risk for HIV if I volunteer for a vaccine clinical trial? 
  9. Is it important to test for HIV across all races and genders? 
  10. When can we expect to have an HIV vaccine? 
  11. Can HIV or AIDS be cured? 

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